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L-Carnitine is a conditionally essential nutrient that supports fat metabolism, energy production and heart health.

In addition, I3C has been demonstrated to upregulate PTEN expression (86) and inhibit the Wnt/-catenin pathway (87) in other tumor types (for example, colorectal and esophageal cancers)

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Methylcobalamin (mB12)/low-dose folinic acid (LDFA) This was a prospective 12-week open-label outpatient treatment trial of subcutaneously injected methylcobalamin (mB12